2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial by John S. Bradley MD, John D. Nelson MD Emeritus

By John S. Bradley MD, John D. Nelson MD Emeritus

This best-selling and common source on pediatric antimicrobial treatment presents fast entry to trustworthy, up to the moment thoughts for therapy of all infectious illnesses in kids. for every disorder, the authors offer a remark to assist wellbeing and fitness care prone pick out the easiest of all antimicrobial offerings. Drug descriptions hide all antimicrobial brokers on hand this day and comprise whole information regarding dosing regimens. based on growing to be matters approximately overuse of antibiotics, this system comprises directions on while to not prescribe antimicrobials. Key positive factors: designed should you look after youngsters and are confronted with judgements on a daily basis; contains therapy of parasitic infections and tropical drugs; up to date anti-infective drug directory, entire with formulations and dosages; and balanced details on protection, efficacy, and tolerability with information on expenditures and availability of drugs.

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Extra resources for 2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial Therapy

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Very poor outcomes. day IM, IV div q8h x 10–14 d (AIII) Ceftriaxone 50 mg/kg q24h IV, IM (AIII) Treatment course x 10–14 d – Staphylococcal Vancomycin 40 mg/kg/day IV div q8h pending susceptibility testing; oxacillin 150 mg/kg/day IV div q6h if susceptible (AIII) – Empiric therapy following Vancomycin 40 mg/kg/day IV div q8h AND ceftazidime open globe injury 150 mg/kg/day IV div q8h (AIII) Endophthalmitis56,57 NOTE: Subconjunctival/subtenon antibiotics usually needed; steroids commonly used; Refer to ophthalmologist; vitrectomy may be necessary for requires anterior chamber or vitreous tap for microbiological diagnosis advanced endophthalmitis Dacryocystitis No antibiotic usually needed; oral therapy for more Warm compresses; may require surgical probing of symptomatic infection, based on Gram stain and nasolacrimal duct culture of pus; topical therapy as for conjunctivitis may be helpful Conjunctivitis, herpetic54,55 Trifluridine 1% ophth soln OR acyclovir 3% ophth Refer to ophthalmologist.

D Higher dosage may be needed for aspergillus than for candida. May also be dosed as 25–50 mg/m2 qd for all age groups. e Cefepime should be given at 60 mg/kg/day div q12h for the first 2 weeks of age, after which the dosing increases to 100 mg/kg/day div q12h. For meningitis or Pseudomonas infections, dosage is 150 mg/kg/day div q8h. f 25–50 mg/kg (maximum 125 mg) as single dose for gonococcal eye prophylaxis or treatment. g Increase to 150/mg/kg/day to achieve serum concentration of 50–70 μg/mL.

OROPHARYNGEAL INFECTIONS Sinusitis, acute Same antibiotic therapy as for AOM (amoxicillin 90 mg/ For more severe symptoms, use high-dosage amox/clav to (H influenzae non–type b, kg/day PO div bid) (BIII). indd 42 Pharyngitis Amoxicillin 50–75 mg/kg/day PO, either once daily, bid Amoxicillin displays better gastrointestinal absorption (group A streptococcus) or tid x 10 d OR penicillin V 50–75 mg/kg/day PO div than oral phenoxymethyl penicillin; the suspension is 7,91–93 tonsillopharyngitis bid or tid, OR benzathine penicillin 600,000 units IM better tolerated.

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